ceesdekker Can Be Fun For Anyone

Nanotechnology presents An array of possibilities to contribute to biology. In this article I'll existing illustrations where nanofabrication – the ability to make confined structures with dimensions at will – is utilized to examine the biophysics of single molecules and cells. I will present some examples from our lab:

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Multicolor imaging of your bacterial nucleoid and mobile division proteins with blue, orange, and around-infrared fluorescent proteins

Nanofabrication of electrodes with sub-five nm spacing for transport experiments on one molecules and metal clusters

De sterke polarisatie in de discussie rond schepping/evolutie en meer algemeen rond geloof/wetenschap lijkt helaas geen eind te kennen. Toch is er wel degelijk een heilzame middenweg, maar deze krijgt about het algemeen weinig aandacht. Dit boek kan hier wellicht verandering in brengen. Wie de geschiedenis van de relatie tussen geloof en wetenschap in duikt, komt tot verrassende inzichten. De moderne mens leeft fulfilled veel stereotypen die historisch niet verantwoord blijken te zijn. Afgezaagde typeringen als ‘Vroeger dachten we dat de

Cornelis (Cees) Dekker (Haren, seven april 1959) is een Nederlandse natuurkundige en universiteitshoogleraar verbonden aan de Technische Universiteit Delft. Van 2010 tot en achieved 2018 was hij tevens directeur van het Kavli Institute of Nanoscience in Delft. Zijn vakgebied is de moleculaire biofysica; hierbij beweegt hij zich op het grensvlak van de natuurkunde en de biologie waarbij hij gebruikmaakt van de zogeheten nanotechnologie, de technieken om aan enkele atomen en moleculen te kunnen meten.

Many associated developments followed, exactly where our group set up distinct transistor variants including solitary-electron transistors at area temperature and intramolecular nanotube junctions that acted as rectifying diodes, and coupled a number of transistors into modest proof-of-theory electronic circuits.

2011, very first in vitro measurements of transport across only one biomimetic nuclear pore elaborate; enhancement of multiplexed magnetic tweezers for kilo-molecule experiments; and solved the system of homology recognition in DNA homologous recombination

Comprehension elementary procedures regulating the spatial and dynamic organisation on the DNA in Stay cells.

Dekker began his research on solitary carbon nanotubes in 1993 when he create a new line of exploration to review electrical transportation by way of single organic and natural molecules in between nanoelectrodes. In 1996 a breakthrough was understood with carbon nanotubes. This was attained in a collaboration Along with the group of Nobel laureate Richard Smalley. STM and nanolithography procedures have been utilized to exhibit that these nanotubes are quantum wires at The one-molecule degree, with fantastic physical Homes.

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2001, discovery of one-electron transistors at place temperature dependant on nanotubes; realization of to start with logic circuits with carbon nanotube equipment; and discovery of the molecular structure of DNA repair enzymes with AFM

Visualization of unstained DNA nanostructures with Superior in-emphasis transmission electron microscopy approaches

Strong-point out nanopores have tested to be a surprisingly versatile probe for single-molecule Assessment of DNA. I will explain several of our latest findings – specifically DNA knots – and our initiatives to increase the capabilities of good-condition nanopores even more, within the way of one-protein detection, graphene ceesdekker nanopores, plasmonic nanopores, and DNA origami nanopores.